Peter Zimmerman, PhD, Professor of International Health, Biology and Genetics, was the first customer to receive the newly launched MAGPIX® instrument in 2010. While his lab is at Case Western Reserve University (CWRU) in Cleveland, Ohio, the instrument was installed at Zimmerman’s field research site in Papua New Guinea.
While the genome is the molecular recipe, the proteome provides a glimpse into what is happening in real time. Like letters that join together to compose ‘words’, individual proteins can bind to form distinctive protein complexes, where the unique composition of each protein complex signals to the cell a specific message. The human genome was sequenced in 2003, but the different combinations that proteins can form remain largely uncharted due to technological limitations.
Although detecting the subtle changes in the proteome is no easy task, the lab of Adam Schrum was up for the challenge. Schrum and colleagues recently published an article in Science Signaling detailing the development of a new method, PiSCES (Proteins in Shared Complexes Detected by Exposed Surface Epitopes), capable of deciphering the molecular signatures unique to healthy and aberrant signaling networks associated with disease.
Barcoding is no longer confined to the black stripes of the ubiquitous Universal Product Code (UPC) label found on nearly every product we purchase. Conservationist Paul Hebert was the first to demonstrate the feasibility and utility of DNA barcoding as a way to identify species in 2003.
Applications outside the research lab include the detection of food fraud, where lower quality fish is substituted for a more desirable species. A recent study by OCEANA found that 39 percent of 142 seafood samples collected and DNA tested from grocery stores, restaurants, and sushi venues in New York City were mislabeled.
Affymetrix Checkmate on Cancer – get the full view soluble immune checkpoint molecules with the ProcartaPlex® Immuno-Oncology Checkpoint Molecules Panel (14pplex).
R&D Systems, a Bio-Techne Brand Want at custom biomarker assay? Don’t want to build it yourself? The Luminex Assay, by R&D Systems, offers 347 biomarkers to select from enabling you to configure the exact assay you need.
MilliporeSigma Researching Parkinson’s Disease, Alzheimer’s Disease, or Traumatic Brain Injury? The MILLIPLEX® MAP Human Neuroscience Magnetic Bead Panel 1 (product number HNS1MAG-95K) is a new 6-plex kit that requires only 25μL of neat human cerebrospinal fluid (CSF) per assay.
In this blog series, you’ve been getting to know some of the employees at Luminex. In today’s Q&A, we profile Christoph Cordes, Senior Director of Marketing & Scientific Applications for Europe, the Middle East, India, and Africa. He’s been with Luminex for 14 years, and has a biology degree and MBA from the University of Texas. In 2015, he and his family moved to the Netherlands to help launch new products in Europe.
Q: What do you do at Luminex?
A: I’ve had lots of different jobs since I joined in 2002. I’ve worked in sales, distributor and partner management, and global marketing. In 2012, I started up a group that was responsible for launch readiness…
Flu season is rapidly approaching. As usual, experts at the U.S. Centers for Disease Control and Prevention recommend getting a flu vaccine by the end of October — but now, they’re calling for only flu shots. Nasal spray vaccines are no longer recommended. This year’s vaccine protects against a cocktail of influenza A and B viruses (see details from the CDC).
Approximately one third of the world’s population is infected with the tuberculosis (TB) bacteria, Mycobacterium tuberculosis Complex (MTBC), which is one of the deadliest infectious diseases world-wide. One of the greatest threats to global TB control is the growing prevalence of drug resistant strains. In 2014, multidrug-resistant TB (MDR-TB) accounted for about 3.3% of new TB cases and 20% of previously treated cases. The need for novel molecular methods to rapidly identify TB is critical.
Verigene diagnostics help doctors respond quickly to life-threatening condition You may associate September wi…
Analyzing a large number of samples or developing a highly multiplexed assay? Consider automating* all or part of your xMAP® workflow.
xMAP Technology provides the flexibility to customize each assay step—for both throughput and multiplexing. Specifically:
A new Virology Journal paper reports the results of a study evaluating the use of our xTAG® Gastrointestinal Pathogen Panel (GPP) for detecting rotavirus in children in Ghana. The xTAG assay is a multiplexed molecular test for viral, parasitic, and bacterial nucleic acids in human stool specimens.